South Park

South Park is an American animated by Trey Parker and Matt Stone and was developed by Bran Graden for Comedy special. Since it first premiered in August 13, 1997, the series has produced 25 episode with 314 episode in total, including a movie in 1999, several specials on Paramount+ and several video games.

The series follows the children of the titular town: Stan Mark, Kenny McCormick, Eric Cartman, and Kyle Broflosky getting into all sorts of wacky hijinks. The series is best known for its crude humor, jokes meant to offend everyone, and the running gag of Kenny dying.

Droopy

 * "Crippled Summer": Droopy is the inspiration for one of the handicapped kids.

Flintstones

 * South Park: The Fractured But Whole: A Flintstones loin cloth can be seen in Sloppy 2nds

Jonny Quest

 * "Imaginationland Part III": a parody of Jonny Quest is seen on the good side.

Laff-A-Lympics

 * "Crippled Summer": The Red and Blue Teams, as well as the "villain" team using crazy ideas to win the race, is very similar to the Laff-A-Lympics.

Scooby-Doo

 * "Korn's Groovy Pirate Ghost Mystery": The band Korn is based off Mystery Inc., even with a Mystery Machine and traps that would put Fred Jones to shame.
 * South Park: The Fractured But Whole: Mystery Inc's clothes can be found at Sloppy 2nds.

Speed Buggy

 * "Imaginationland Part III": a parody of Speed Buggy is seen on the good guys side.

Smurfs

 * "Imaginationland Part III": A smurf is seen on the good guys side.

Quick Draw McGraw

 * "Imaginationland Part III": A parody of Quick Draw McGraw and Baba Looey is seen on the good side. They are both immediately ambushed by the bad guys but show up in a later scene completely fine.

Wacky Races

 * "Handicar": Dick Dastardly and Muttley attempt to cheat the race by cutting down the trees to block the path. It doesn't work and their car ends up getting stolen.
 * South ParQ Vaccination Special: Dastardly and Muttley can be seen celebrating the end of the Pandemic. It's worth nothing that in both of their appearences, Dastardly and Muttley are drastically older than their original counterparts.

Other

 * "Crippled Summer": Niblit is meant to be a parody of various Hanna-Barbera animal sidekicks such as Gleek and Jabberjaw.